Organic Synthesis
BASIC DATA
course listing
A - main register
course code
LKK0050
course title in Estonian
Orgaaniline süntees
course title in English
Organic Synthesis
course volume CP
-
ECTS credits
6.00
to be declared
yes
fully online course
not
assessment form
Examination
teaching semester
spring
language of instruction
Estonian
English
The course is a prerequisite
Study programmes that contain the course
code of the study programme version
course compulsory
no
Structural units teaching the course
LK - Department of Chemistry and Biotechnology
Timetable link
Version:
VERSION SPECIFIC DATA
course aims in Estonian
Aine eesmärk on:
- tutvustada põhilisi orgaanilise sünteesi ja retrosünteetilise analüüsi meetodeid;
- anda ülevaade nende rakendamisest konkreetsete funktsionaalrühmade muundamistel ja keerulisemate ühendite sünteesi planeerimisel.
- tutvustada põhilisi orgaanilise sünteesi ja retrosünteetilise analüüsi meetodeid;
- anda ülevaade nende rakendamisest konkreetsete funktsionaalrühmade muundamistel ja keerulisemate ühendite sünteesi planeerimisel.
course aims in English
The aim of this course is to:
- introduce essential organic synthesis and retrosynthetic analysis;
- provide an overview of functional group transformations and their application in planning the synthesis of complex molecules.
- introduce essential organic synthesis and retrosynthetic analysis;
- provide an overview of functional group transformations and their application in planning the synthesis of complex molecules.
learning outcomes in the course in Est.
Õppeaine läbinud üliõpilane:
- rakendab orgaanilise sünteesi põhiprintsiipide sünteesi planeerimiseks;
- tunneb tähtsamaid C-C sidemete tekitamise lähenemisi ja funktionaalrühmade manipulatsioone (sh kaitsvaid rühmi ja nende keemiat);
- põhjendab reagentide valikut konkreetse sünteesietapi teostamiseks;
- eristab kasulikke ja kasutuid retrosünteetilisi katkestusi.
- rakendab orgaanilise sünteesi põhiprintsiipide sünteesi planeerimiseks;
- tunneb tähtsamaid C-C sidemete tekitamise lähenemisi ja funktionaalrühmade manipulatsioone (sh kaitsvaid rühmi ja nende keemiat);
- põhjendab reagentide valikut konkreetse sünteesietapi teostamiseks;
- eristab kasulikke ja kasutuid retrosünteetilisi katkestusi.
learning outcomes in the course in Eng.
After completing this course, the student:
- applies the main principles of synthetic organic chemistry to synthesis planning;
- knows the most important approaches for C-C bond formation and functional group manipulations (including protecting groups and their chemistry);
- is able to justify the choice of reagent for a specific synthetic step;
- can distinguish between productive and unproductive retrosynthetic disconnections.
- applies the main principles of synthetic organic chemistry to synthesis planning;
- knows the most important approaches for C-C bond formation and functional group manipulations (including protecting groups and their chemistry);
- is able to justify the choice of reagent for a specific synthetic step;
- can distinguish between productive and unproductive retrosynthetic disconnections.
brief description of the course in Estonian
Orgaanilise sünteesi eesmärgid. Funktsionaalsete rühmade saamise ja teisendamise põhilised meetodid. Retrosüntees: sihtühendi liigitamine süntoniteks - nende sünteetilised ekvivalendid. Funktsionaalsete rühmade kaitsmine keemilises sünteesis – alkoholide, aldehüüdide, karboksüülhapete ja amiinide kaitsmine. C-C sideme moodustamine karbanioonide ja karbakatioonide abil. Radikaalreaktsioonid, taandamise ja oksüdeerimise meetodid. Asümmeetrilise sünteesi põhiprintsiibid.
brief description of the course in English
Main goals of organic synthesis. General methods of obtaining and transformations of functional groups. Retrosynthesis: synthons and their syntetic equivalents. Protection of functional groups (alcohols, carboxylic acids, carbonyl compounds, amines). Formation of C-C bond with carbanions and carbocations. Radical reactions, main methods of oxidation and reduction. Basic principles of asymmetric synthesis.
type of assessment in Estonian
Eksam
type of assessment in English
Examination
independent study in Estonian
Kodune töö sünteesiülesannetega
independent study in English
Homework - synthetic problems
study literature
Smith, M.B. Organic synthesis, McGraw-Hill 1994, 2002
Smith, M. B. Organic synthesis, Elsevier 2016
teadusartiklid
Smith, M. B. Organic synthesis, Elsevier 2016
teadusartiklid
study forms and load
daytime study: weekly hours
4.0
session-based study work load (in a semester):
lectures
2.0
lectures
-
practices
0.0
practices
-
exercises
2.0
exercises
-
lecturer in charge
Mikk Kaasik, vanemteadur (LK - keemia ja biotehnoloogia instituut)
LECTURER SYLLABUS INFO
semester of studies
teaching lecturer / unit
language of instruction
Extended syllabus
2024/2025 spring
Mikk Kaasik, LK - Department of Chemistry and Biotechnology
Estonian